cfaed Seminar Series

Dr. Ivan Minev , BIOTEC, TU Dresden

Electronic Tissue Technologies for Interfacing and Repair of the Nervous System

08.12.2016 (Thursday) , 13:00 - 14:00
Seminar Room 115 (HAL) , Hallwachsstr. 3 , 01187 Dresden

Bioelectronic medicine may soon enable the restoration of body functions lost in injury or
disease. This will have high impact in the nervous system, where failure of self-repair
following trauma, stroke or neurodegeneration can have profound and permanent
consequences on the patient’s quality of life. Implanted systems will deliver, tune and
coordinate a therapeutic program consisting of electrical impulses, drugs, light, or
replacement cells. The realization of this vision is hindered by the lack of an implantable
technology that can blend with the host organ and deliver such complex functionality.
In this talk, I will summarize my experience in building neuroprosthetic implants. I will
emphasize on the materials and technologies used for fabricating devices that not only
integrate with mechanically delicate neural tissues but also deliver multi-modal
neuromodulation. We created an artificial membrane that mimics the mechanical
properties of dura mater - the protective skin around the brain and spinal cord - and
integrated nanocomposite electrodes, thin-film interconnects and microfluidics to enable its
functionality. Chronically implanted on the surface of the spinal cord, the electronic dura
mater was used to restore walking in rats with paralyzing spinal cord injury by delivering
precise electro-chemical stimulation to the dormant spinal cord [1]. Finally, I will discuss
how bioelectronic systems can be harnessed to repair the injury and possibly deliver a
permanent therapeutic effect.

Ivan Minev received the MSci degree in Physics from Imperial College London
in 2008. He obtained the PhD degree from the Department of Electrical
Engineering at the University of Cambridge in 2012. From 2012 to 2016 he was
post-doctoral researcher at the Center for Neuroprosthetics in EPFL, the Swiss
Federal Institute of Technology in Lausanne.
He has co-organized several symposia on the topic of soft bioelectronics as
part of the Materials Research Society Spring Meetings in San Francisco and
In 2016, Ivan received the Freigeist fellowship from the Volkswagen Stiftung
and is now leading the “Electronic Tissue Technologies” group at TU Dresden’s
BIOTEC center.

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