cfaed Seminar Series

Abstract

There is a strong impetus for the development of biomaterials directed for medical applications. In particular, nanocarriers delivering therapeutic agents such as drugs and nucleic acids is attracting significant attention as targeted therapy, often called Nanomedicine. We have developed supramolecular “smart” nanocarriers through self-assembly process from functional block copolymers and have demonstrated therapeutic effect by facilitating the translation of basic achievements into clinical applications. Gene therapy is one of the most challenging targets owing to its extremely high therapeutic potency, which achievement entirely relies on an establishment of safe and effective delivery system.

This talk will focus the development of smart block copolymer-based gene delivery system, in particular, for systemic application to treat intractable cancers.