Biological Algorithms Group

Our mission is to identify simple paradigms of robust motility control and pattern formation in complex biological systems. We reverse-engineer biological solutions of robust control in close collaboration with experimental biologists. We use tools from physics, information theory, and engineering; likewise, we seek to excite bio-inspired applications of biological information processing in these fields.

We focus on principles of biological information processing in two model systems:

  1. Motility control: We study how noisy sensory information controls biological motility and dynamic decision making, e.g. during sperm navigation to the egg.
  2. Pattern control: We study elementary rules of self-organized pattern formation during self-repair and adaptation, e.g. of load-balancing transport networks in the liver.

On top of that, we explore potential applications of biological control designs in advanced electronics applications in tight collaboration with the other paths of the cfaed.

We are currently searching for highly motivated and talented students to work at the interface of physics and biology with a twist towards computer science.

Group News

Lehre Sommersemester 2020 [corona update]

betrifft "Theoretische Mechanik für das Lehramt"

Published on in BIOLOGICAL ALGORITHMS (NEWS)

Alle Studierende der Vorlesung "Theoretische Mechanik für das Lehramt SS20", bitte melden Sie sich im OPAL-System an und registrieren sich beim Online-Auftritt der Vorlesung.

https://bildungsportal.sachsen.de/opal/auth/RepositoryEntry/22844866560;jsessionid=82D01774297194780C4331668AB3D754.opalN6?0

Hier werden wir Informationen bereitstellen und in den nächsten Wochen ein Online-Lehrangebot erstellen.

New PRL on Chemokinesis

Chemokinetic Scattering, Trapping, and Avoidance of Active Brownian Particles

Published on in BIOLOGICAL ALGORITHMS (NEWS)

New Physical Review Letters on chemokinesis, providing a full theory of spatially inhomogeneous search, relevant for chemotaxis with noise: if you know a hidden target is close, but have no information on direction, how to search best?

https://journals.aps.org/prl/abstract/10.1103/PhysRevLett.124.118101

New preprint: Bayesian gradient sensing in the presence of rotational diffusion

Published on in BIOLOGICAL ALGORITHMS (NEWS)

Biological cells sense chemical gradients: molecular counting noise, but also the cell's own stochastic motion, limit the precision. New preprint on the 'physical limits of chemosensation' if cells suffer both sensing and motility noise https://arxiv.org/pdf/2002.08138.pdf

 

Steffen Lange leaves the team to start his own group!

Published on in BIOLOGICAL ALGORITHMS (NEWS)

Steffen Lange leaves the team and is now research group leader of an ESF junior research group project. The project is called 'DataMedAssist' and examines innovative Data-Science methods for the Systems medicine, in particular assistance in the analysis of multicellular tissue organisation. Four PhD students are part of Steffens group belonging to Prof. Voss-Boehme at HTW Dresden.

We wish Steffen Lange good luck and a successful project!

Two new preprints before Christmas

"Fertilization in the sea: sperm chemotaxis in physiological shear flows" and "Resilience of three-dimensional sinusoidal networks in liver tissue"

Published on in BIOLOGICAL ALGORITHMS (NEWS)

We are hiring!

Post-doc on Information theory of navigation in complex, time-varying environments

Published on in BIOLOGICAL ALGORITHMS (NEWS)

We welcome Francine Kolley and Ian Eastabrook to our group!

Francine and Ian will work on self-assembly of active force-generating myofibrils in muscle cells, a striking example of a "biological crystal" (funding by HFSP)

Published on in BIOLOGICAL ALGORITHMS (NEWS)

We are growing: welcome to Maja Grützmann and Elena Erben

Elena joined to work as research assistant on modeling information processing in artificial cells, Maja will do her Bachelor thesis on synchronization of coupled noisy oscillators: welcome!

Published on in BIOLOGICAL ALGORITHMS (NEWS)

We welcome Iaroslav Babenko to our group!

Iaroslav started as predoc to unravel the rules that guide the self-assembly of functional biomineral patterns of diatom silica shells

Published on in BIOLOGICAL ALGORITHMS (NEWS)

Read more …

Group outing to Swiss Saxony

Farewell to our summer intern Lidiia Nadporozhskaia (who did an impressing analysis of spermbot motility)

Published on in BIOLOGICAL ALGORITHMS (NEWS)