cfaed Publications

Thermophoretic trapping and manipulation of single molecules

Reference

Marco Braun, Tobias Thalheim, Katrin Günther, Michael Mertig, Frank Cichos, "Thermophoretic trapping and manipulation of single molecules" , vol. 9922, pp. 9922-9922, 2016. [doi]

Abstract

We demonstrate the long time trapping of single DNA molecules in liquids by feedback driven dynamic temperature fields. By spatially and temporally varying the temperature at a plasmonic nanostructure, thermophoretic drifts are induced that are used to trap single nano-objects. A feedback controlled switching of local temperature fields allows us to confine the motion of a single DNA molecule for minutes. The DNA conformation and conformation dynamics are analyzed in terms of a principle component analysis. Current results are in agreement with previous measurements in thermal equilibrium and suggest only a weak influence of the inhomogeneous temperature rise on the structure and dynamics in the trap.

Bibtex

@proceedings{doi: 10.1117/12.2239481,
author = {Braun, Marco and Thalheim, Tobias and Günther, Katrin and Mertig, Michael and Cichos, Frank},
title = {Thermophoretic trapping and manipulation of single molecules},
journal = {Proc. SPIE.},
volume = {9922},
pages = {9922 - 9922 - 8},
abstract = {We demonstrate the long time trapping of single DNA molecules in liquids by feedback driven dynamic temperature fields. By spatially and temporally varying the temperature at a plasmonic nanostructure, thermophoretic drifts are induced that are used to trap single nano-objects. A feedback controlled switching of local temperature fields allows us to confine the motion of a single DNA molecule for minutes. The DNA conformation and conformation dynamics are analyzed in terms of a principle component analysis. Current results are in agreement with previous measurements in thermal equilibrium and suggest only a weak influence of the inhomogeneous temperature rise on the structure and dynamics in the trap.},
year = {2016},
doi = {10.1117/12.2239481},
URL = {http://dx.doi.org/10.1117/12.2239481},
}

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